Cytosolically expressed PrP GPI-signal peptide interacts with mitochondria
نویسندگان
چکیده
منابع مشابه
Cytosolically expressed PrP GPI-signal peptide interacts with mitochondria
We previously reported that PrP GPI-anchor signal peptide (GPI-SP) is specifically degraded by the proteasome. Additionally, we showed that the point mutation P238S, responsible for a genetic form of prion diseases, while not affecting the GPI-anchoring process, results in the accumulation of PrP GPI-SP, suggesting the possibility that PrP GPI-anchor signal peptide could play a role in neurodeg...
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ژورنال
عنوان ژورنال: Communicative & Integrative Biology
سال: 2015
ISSN: 1942-0889
DOI: 10.1080/19420889.2015.1036206